Provail® Technology and Benefits*

When it comes to healthy cellular aging and immune function, glutathione—a potent antioxidant found in the human body—is amongst our most powerful tools.* The supplement technology to unlock its potential by increasing glutathione levels in the bloodstream is finally available.*

While glutathione is teeming with benefits, premature digestive breakdown and sub-par absorption are common drawbacks of glutathione supplementation.* Despite mega-dosing and other attempts to see helpful results, most glutathione supplementation efforts have fallen short. However, the efficient glutathione delivery system integrative practitioners and health-conscious consumers have been waiting for is finally here: whey protein-encapsulated glutathione.* DaVinci®  Laboratories’ Provail® helps ensure this antioxidant gets where it’s most needed for optimal absorption and utilization.*

Challenges to Glutathione Supplementation

Glutathione, often referred to as the body’s master antioxidant, plays a vital role in cellular health, immune support, and healthy detoxification pathway performance.* It’s an essential nutrient in phase II detoxification, helping clear harmful toxic byproducts from your cells and helping protect the mitochondria from oxidative damage.*

Traditionally, glutathione supplements were easily broken down into poorly absorbed fragments, making supplementation difficult.^[1] These challenges are compounded by the fact that many supplements on the market contain highly unstable “oxidized” glutathione, which has poor bioavailability.* Higher-quality supplements utilize a more stable, “reduced” version of glutathione; however, it is still prone to premature digestive breakdown and poor absorption.*

Provail® technology revolutionizes glutathione supplementation by offering a higher absorption potential, which can allow intact glutathione to be safely transported and delivered to the small intestine—the only way to benefit from its full range of antioxidant benefits.

What is Provail®?

DaVinci Laboratories prioritized Provail® application to difficult-to-absorb nutrients.* DaVinci® prioritized its application for glutathione because many practitioners are actively seeking clinical results associated with this beneficial antioxidant.*

Glutathione must survive the harsh intestinal tract to be a useful supplement for cellular health.* For a long time, professionals wondered if any amount of glutathione was absorbed from oral supplements, as plasma levels failed to rise in most studies. We now know that some amount is absorbed as pure glutathione, but the amount is still less than clinicians would like to see.^[2]

Provail® is a true game changer when it comes to glutathione absorption.* As a patented technology that uses a state-of-the-art processing technique called whey protein encapsulation, this novel nutrient delivery system more than doubles the amount of absorbable glutathione the body can utilize from each dose, and one study has seen its superiority in helping to boost immunity, supporting digestion and cognitive health, and promoting healthy cellular activity.^[3]

What is Whey Microencapsulation?

The Provail® technology is advanced in its process. First, whey protein undergoes a series of physico-chemical reactions, which result in beneficial structural changes that transform the proteins into a matrix of ultra-small particles, 150-300 nanometers in diameter. Now called polymerized whey protein, this matrix coats the nutrient (in this case, glutathione) to protect it from degradation. You can think of this protective layer as an envelope that helps to carry the nutrient safely through the harsh conditions of the digestive tract, opening to release it for maximum absorption in the small intestine.*

Capable of enveloping micronutrients and releasing them at precisely the right time, in exactly the right place along the gastrointestinal system, Provail® polymerized whey protein is truly ground-breaking.* One study found that Provail® polymerized whey protein-based glutathione delivery system was more effective than leading pure glutathione products in its ability to “improve bioavailability and antioxidant capacity.”*^[4] Along with significantly boosted bioavailability, we know that whey protein encapsulation increases the nutrient’s clinical efficacy and extends its stability by resisting oxidation—one of the many benefits of taking Glutathione with Provail®.^[5]*

Advantages of Glutathione with Provail®* 

Lower Dose

Because of its enhanced absorption, the dosage of Glutathione with Provail® microencapsulation is half that of other leading glutathione supplements.^[6]* More specifically, each capsule contains the recommended dosage of 200 mg of Provail® Glutathione. The research shows that this dose is lower than other leading glutathione products on the market and more substantially raises plasma levels.*^[7]

Heightened Antioxidant Activity*

Compared with a leading competitor, Glutathione with Provail® showed a 2.5x higher maximum plasma glutathione concentration and heightened blood antioxidant activity in animals treated with whey-encapsulated glutathione—all at a faster rate than standard glutathione supplements.*^[8]

Improved Gut and Musculoskeletal Health*

Whey protein in and of itself supports musculoskeletal health, helps to fortify the gut lining, aids in the normal removal of harmful substances, promotes arterial flexibility, and fosters cognitive function*. These benefits also apply when whey is used as a nutrient delivery system.*^[9],^[10]

Provail® allows your glutathione supplement—as well as other tough-to-absorb nutraceuticals—to get to work quickly and efficiently, which can help achieve overall wellness.

Who Should Take Glutathione with Provail®?

Glutathione supplementation is particularly important for individuals with known exposure to heavy metals, people with compromised immune systems, and those struggling with concentration and focus.*

Glutathione with Provail® is beneficial for these groups because its delivery system is clean and simplified, unlike most other glutathione supplements. Whey protein, glutathione, cellulose, and leucine are the only ingredients in Glutathione with Provail®. This isn’t true for most liposomal glutathione supplements that commonly contain carriers and additional inactive ingredients. Plus, it doesn’t need to be refrigerated.

Glutathione with Provail® is free of hormones and gluten. However, people with a milk-related allergy should consult a functional doctor to see if the whey protein formulation is suitable for them.*

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Conclusion

It’s no secret that optimal glutathione levels are a must for healthy cellular aging and detoxification.* Doctors and patients alike have been waiting for a new way to overcome the barriers to absorption.

Glutathione with Provail® technology has revolutionized glutathione supplementation for health-conscious consumers and integrative practitioners. It tackles the challenges of glutathione supplementation head-on, delivering this vital antioxidant with unprecedented efficiency and impact. With a lower dosage and superior absorption, it offers a more potent and bioavailable solution than standard glutathione supplements.*

Thanks to the unique benefits of whey protein encapsulation, Glutathione with Provail® also helps to deliver musculoskeletal support, fortification of the gut lining, and cognitive support.* This clean and simplified supplement holds immense promise, and we are thrilled to witness its possibilities unfold.